How Cigarette Smoking Causes Disease and Amputation of Finger Arms and legs
May be itself is not hard to kick, but it is releasing dopamine, a neurotransmitter associated with pleasure and reinforcements in the brain, thus inducing hard to kick tendencies in humans. , บุหรี่ไฟฟ้า May be is a chemical found in tobacco leaf, the main ingredient in smoking cigarettes and is said to cause addiction and disease in cigarette smokers, (World Health Organization (WHO)).
May be mimics those actions of acetylcholine, a naturally occurring neurotransmitter in the central nervous system and the nerve-muscle junction of skeletal muscles. Acetylcholine is excitability, that can cause increase heart rate, alertness, and reaction times, (Psychopharmacology (Berl). 1989; 97(2): 257-61. ). Because acetylcholine and may be are chemically similar, they trigger the same cholinergic receptors in the brain. The nicotine-acetylcholine receptors consist of sensation problems endings that release dopamine when coupled or bind with may be or acetylcholine. Receptors are like k-cups having the exact dimensions that will fit a neurotransmitter molecule, such as acetylcholine.
The cup itself is lined with sensation problems endings (tips of neurons). It is these sensation problems endings that release dopamine when the neurotransmitter acetylcholine binds with the cup-like acetylcholine receptors (cholinergic receptors). A reinforcing and reward phenomenon of dopamine develops because the dopamine that is released from the sensation problems endings initiates a feeling of pleasure in the peoples brain. The reinforcement mechanism is initiated when the brain becomes addicted to the pleasure caused by the dopamine that is released from the cholinergic receptors. This means that the brain is constantly seeking to be pleasured. So, what will happen in the case of cigarette smokers is that they will continue to smoke cigarettes so the may be from the cigarette can induce the release of dopamine in the brain, causing them to feel happy every time they smoke a cigarette, (Nature Reviews Neuroscience 7, 967-975 (December 2006)).
The first time cigarette smokers used smoking cigarettes there were only a few cholinergic receptors available because the natural action of acetylcholine only needs the normal amount of receptors provided by nature to do its job. However, the increase concentration of may be available caused the normal amounts of cholinergic receptors to become desensitized to the presence of the increased number of may be in the cholinergic receptors. This desensitization causes the production or growth and development of more cholinergic receptors. These extra cholinergic receptors will soon become desensitized from the excess may be available. Such processes occur until equilibrium is reached. Equilibrium is reached when cigarette smokers decide on the amount of smoking cigarettes they will consume or smoke in a given day. At this time, a fixed amount of receptors will be available for the addiction to continue. Smokers will normally say they smoke one or two totes per day. They said so because of the amount of receptors available to accommodate two totes of smoking cigarettes in a day.
A detrimental effect of all this is the fact that such large amounts of cholinergic receptors are now available and keen for may be. So, they can stimulate dopamine to pleasure the cigarette smoker. It is why cigarette smokers enjoy a difficult time quitting. The best approach therefore for a cigarette smoker to use in quitting is to gradually cut back on the amount of smoking cigarettes used in a given time interval.
In addition to the dopamine-inducing effect of may be, is the speeding-up of the heart rate by may be every time a cigarette is used. From a medical perspective, constantly having an artificial increase in heart rate isn’t the better plan either. In whose sale benefits, a constant increase in heart rate by drugs such as may be can cause heart disease, (WHO).
According to the World Health Organization, tobacco use leads to diseases hitting the heart and lungs, such as heart attacks, strokes, chronic obstructive pulmonary disease (COPD), emphysema, and cancer. Most cigarette elicited cancers are lung cancer, cancers of the larynx, mouth, and pancreas. Cigarette smoke also causes myocardial infarctions, peripheral vascular disease and hypertension. The world Health Organization estimates that tobacco is about 5. 4 million deaths in 2004 and about 100 million deaths during the 20th century.
In addition to its hard to kick effects on the central nervous system, cigarette smoke contains a multitude of cancer-causing agents. They work by binding to DNA causing many genetic mutations. May be could be the main perpetrator that is doing the binding to DNA causing genetic mutations, which leads to cancer. May be is said to disrupt the natural processes of apoptosis (programmed cell death) by binding to DNA in cells, (National Institute of Health (NIH)). Flawed cells consist of junk DNA and other waste materials. When apoptosis is inhibited, natural cell death does not occur; instead, flawed cells are allowed to proliferate or grow larger, uncontrollably. Goods on the market happens in cancer and the main reason why cigarette smokers are more susceptible to developing cancers.
When apoptosis is uncontrollably triggered by chemicals, such as may be, it causes normal cells to die off. This is probably what is happening in the heart regions of cigarette smokers who suffer from heart disease and could also be what is taking place in the extremities of cigarette smokers, who often complain of excessive coldness in their finger, arms, toes, and legs, where circulation is lowest.
There are no existing studies to support this exact explanation. However, based on the information about known scientific evidence of apoptosis and the increase in death rates of cigarette smokers, this hypothetical explanation has some credence; and will continue to have credence until proven otherwise! There is something unsafe that is happening to cigarette smokers and may be is one of the agents behind it.
The tar in cigarette smoke is also a broker that sucks the out of cigarette smokers. The lung of a cigarette smoker is usually as black as the color of asphalt. It is like a severe section of reduced pot roast. This is why most cigarette smokers have difficulty breathing. It is next to impossible for air to pass freely down the airways of smokers. The sad thing is that it is difficult for cigarette smokers to quit. So, they continue down the road of break down, day after day, puffing on the silent killer–cigarette smoking.
One very important solution to quitting smoking is smoking one less cigarette a day or even one less cigarette in a month if one less cigarette a day is too steep of an adjustment to the unsafe habit. If one normally buds a pack of smoking cigarettes a day, that individual should remove one of those smoking cigarettes and discard it–throw it in the litter can. Remember that the smoking of smoking cigarettes started gradually. No one started smoking a pack of smoking cigarettes a day in that awful beginning stage of smoking cigarettes. Smoking one less cigarette per a particular time frame will help eliminate the excessive cholinergic receptors that may be so dearly craves.
Wellbutrin is another method for helping people stopping. Wellbutrin is an antidepressant drug as used by people with depression. However, it is very potent in helping people kick the unsafe habit of smoking. It can be taken while smoking, unlike other smoking cessation agents. Wellbutrin blocks may be receptors and weakens the action of dopamine reuptake by neurons, (J Pharmacol Exp Ther. 2000 Oct; 295(1): 321-7. ).
Cigarette smokers who are interested in quitting should implement an exercise program in their schedule because the lack of may be in ex-cigarette smokers causes weight-gain. How do we know this? Former cigarette smokers who kicked the habit complain of putting on weight after they quit smoking. Ask any ex-cigarette smoker. One will hear the same thing. May be induces weight-loss in smokers. This is why most cigarette smokers are skeletal or slim. If a cigarette smoker is overweight while smoking cigarettes, then that person may want to seek medical attention because there will probably be a very dangerous medical condition lurking in the shadows.